The Human Microbiome and its Role in Immunity

Abstract

The human microbiome or, to be precise, a group of trillions of microorganisms inhabiting the human body is essential to the mechanisms of physiological homeostasis and immune regulation. The interaction between the host and the microbial communities is complex, which defines the immune system development and the disease development and progression. The paper will discuss the interaction between the human microbiome and immune response in terms of the immunoprotective and immunopathological effects. The paper examines the awareness, perception, and knowledge of the role of microbiome in immunity using a primary data survey of 200 participants (clinicians, researchers and general respondents). On the one hand, the statistically obtained results have revealed the close relationship between the inoculation of the microbiome and the strength of the immune system, and on the other hand, the dietary regimen and antibiotic use. The findings demonstrate the potential of microbiome-directed treatment in the management of autoimmune diseases, allergies, and infections. However, issues of variability between individuals, data and clinical interpretation still exist.